Isodeoxyelephantopin induces protective autophagy in lung cancer cells via Nrf2-p62-keap1 feedback loop

Isodeoxyelephantopin (ESI), isolated from Elephantopus scaber L. has been reported to exert anticancer effects. In this study, we aimed to investigate whether and how cancer cells exert protective responses against ESI treatment. Confocal fluorescence microscopy showed that ESI significantly induced...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Cell Death Dis
Hauptverfasser: Wang, Yang, Zhang, Jing, Huang, Zhi-Hao, Huang, Xiao-Hui, Zheng, Wei-Bin, Yin, Xing-Feng, Li, Yao-Lan, Li, Bin, He, Qing-Yu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584574/
https://ncbi.nlm.nih.gov/pubmed/28617433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.265
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