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Isodeoxyelephantopin induces protective autophagy in lung cancer cells via Nrf2-p62-keap1 feedback loop

Isodeoxyelephantopin (ESI), isolated from Elephantopus scaber L. has been reported to exert anticancer effects. In this study, we aimed to investigate whether and how cancer cells exert protective responses against ESI treatment. Confocal fluorescence microscopy showed that ESI significantly induced...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, Yang, Zhang, Jing, Huang, Zhi-Hao, Huang, Xiao-Hui, Zheng, Wei-Bin, Yin, Xing-Feng, Li, Yao-Lan, Li, Bin, He, Qing-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584574/
https://ncbi.nlm.nih.gov/pubmed/28617433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.265
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