Isodeoxyelephantopin induces protective autophagy in lung cancer cells via Nrf2-p62-keap1 feedback loop

Isodeoxyelephantopin (ESI), isolated from Elephantopus scaber L. has been reported to exert anticancer effects. In this study, we aimed to investigate whether and how cancer cells exert protective responses against ESI treatment. Confocal fluorescence microscopy showed that ESI significantly induced...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Wang, Yang, Zhang, Jing, Huang, Zhi-Hao, Huang, Xiao-Hui, Zheng, Wei-Bin, Yin, Xing-Feng, Li, Yao-Lan, Li, Bin, He, Qing-Yu
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584574/
https://ncbi.nlm.nih.gov/pubmed/28617433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.265
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