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Acidic pH is essential for maintaining mast cell secretory granule homeostasis

It has been recognized for a long time that the secretory granules of mast cells are acidic, but the functional importance of maintaining an acidic pH in the mast cell granules is not fully understood. Here we addressed this issue by examining the effects of raising the pH of the mast cell secretory...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Pejler, Gunnar, Hu Frisk, Jun Mei, Sjöström, Daniel, Paivandy, Aida, Öhrvik, Helena
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584528/
https://ncbi.nlm.nih.gov/pubmed/28492555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.206
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