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Acidic pH is essential for maintaining mast cell secretory granule homeostasis

It has been recognized for a long time that the secretory granules of mast cells are acidic, but the functional importance of maintaining an acidic pH in the mast cell granules is not fully understood. Here we addressed this issue by examining the effects of raising the pH of the mast cell secretory...

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Publicat a:Cell Death Dis
Autors principals: Pejler, Gunnar, Hu Frisk, Jun Mei, Sjöström, Daniel, Paivandy, Aida, Öhrvik, Helena
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584528/
https://ncbi.nlm.nih.gov/pubmed/28492555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.206
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