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Accurate RNA consensus sequencing for high-fidelity detection of transcriptional mutagenesis-induced epimutations
Transcriptional mutagenesis (TM) due to misincorporation during RNA transcription can result in mutant RNAs, or epimutations, that generate proteins with altered properties. TM has long been hypothesized to play a role in aging, cancer, and viral and bacterial evolution. However, inadequate methodol...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5584456/ https://ncbi.nlm.nih.gov/pubmed/28798064 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1709166114 |
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