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Two transmembrane dimers of the bovine papillomavirus E5 oncoprotein clamp the PDGF β receptor in an active dimeric conformation

The dimeric 44-residue E5 protein of bovine papillomavirus is the smallest known naturally occurring oncoprotein. This transmembrane protein binds to the transmembrane domain (TMD) of the platelet-derived growth factor β receptor (PDGFβR), causing dimerization and activation of the receptor. Here, w...

詳細記述

保存先:
書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Karabadzhak, Alexander G., Petti, Lisa M., Barrera, Francisco N., Edwards, Anne P. B., Moya-Rodríguez, Andrés, Polikanov, Yury S., Freites, J. Alfredo, Tobias, Douglas J., Engelman, Donald M., DiMaio, Daniel
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584431/
https://ncbi.nlm.nih.gov/pubmed/28808001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1705622114
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