BRD4 facilitates DNA damage response and represses CBX5/Heterochromatin protein 1 (HP1)

Ovarian cancer (OC) is a heterogeneous disease characterized by defective DNA repair. Very few targets are universally expressed in the high grade serous (HGS) subtype. We previously identified that CHK1 was overexpressed in most of HGSOC. Here, we sought to understand the DNA damage response (DDR)...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Pongas, Georgios, Kim, Marianne K., Min, Dong J., House, Carrie D., Jordan, Elizabeth, Caplen, Natasha, Chakka, Sirisha, Ohiri, Joyce, Kruhlak, Michael J., Annunziata, Christina M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2017
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584257/
https://ncbi.nlm.nih.gov/pubmed/28881656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17572
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