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Structural basis of HP1/PXVXL motif peptide interactions and HP1 localisation to heterochromatin

HP1 family proteins are adaptor molecules, containing two related chromo domains that are required for chromatin packaging and gene silencing. Here we present the structure of the chromo shadow domain from mouse HP1β bound to a peptide containing a consensus PXVXL motif found in many HP1 binding par...

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Main Authors: Thiru, Abarna, Nietlispach, Daniel, Mott, Helen R, Okuwaki, Mitsuru, Lyon, Debbie, Nielsen, Peter R, Hirshberg, Miriam, Verreault, Alain, Murzina, Natalia V, Laue, Ernest D
格式: Artigo
語言:Inglês
出版: 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1271814/
https://ncbi.nlm.nih.gov/pubmed/14765118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600088
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