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Structural basis of HP1/PXVXL motif peptide interactions and HP1 localisation to heterochromatin

HP1 family proteins are adaptor molecules, containing two related chromo domains that are required for chromatin packaging and gene silencing. Here we present the structure of the chromo shadow domain from mouse HP1β bound to a peptide containing a consensus PXVXL motif found in many HP1 binding par...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Thiru, Abarna, Nietlispach, Daniel, Mott, Helen R, Okuwaki, Mitsuru, Lyon, Debbie, Nielsen, Peter R, Hirshberg, Miriam, Verreault, Alain, Murzina, Natalia V, Laue, Ernest D
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1271814/
https://ncbi.nlm.nih.gov/pubmed/14765118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600088
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