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Identification of deubiquitinase targets of isothiocyanates using SILAC-assisted quantitative mass spectrometry

Cruciferous vegetables such as broccoli and kale have well documented chemopreventative and anticancer effects that are attributed to the presence of isothiocyanates (ITCs). ITCs modulate the levels of many oncogenic proteins, but the molecular mechanisms of ITC action are not understood. We previou...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Lawson, Ann P., Bak, Daniel W., Shannon, D. Alexander, Long, Marcus J.C., Vijaykumar, Tushara, Yu, Runhan, Oualid, Farid El, Weerapana, Eranthie, Hedstrom, Lizbeth
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584250/
https://ncbi.nlm.nih.gov/pubmed/28881649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17261
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