Dimerization of EGFR and HER2 induces breast cancer cell motility through STAT1-dependent ACTA2 induction

The dimerization of EGFR and HER2 is associated with poor prognosis such as induction of tumor growth and cell invasion compared to when EGFR remains as a homodimer. However, the mechanism for events after dimerization in breast cancer models is not clear. We found that expressions of alpha-smooth m...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Jeon, Myeongjin, You, Daeun, Bae, Soo Youn, Kim, Seok Won, Nam, Seok Jin, Kim, Hyeon Ho, Kim, Sangmin, Lee, Jeong Eon
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584169/
https://ncbi.nlm.nih.gov/pubmed/28881584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10843
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