A functional comparison between the HER2(high)/HER3 and the HER2(low)/HER3 dimers on heregulin-β1-induced MMP-1 and MMP-9 expression in breast cancer cells

Overexpression of HER2 correlates with more aggressive tumors and increased resistance to cancer chemotherapy. However, a functional comparison between the HER2(high)/HER3 and the HER2(low)/HER3 dimers on tumor metastasis has not been conducted. Herein we examined the regulation mechanism of heregul...

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Bibliografiske detaljer
Main Authors: Kim, Sangmin, Han, Jeonghun, Shin, Incheol, Kil, Won Ho, Lee, Jeong Eon, Nam, Seok Jin
Format: Artigo
Sprog:Inglês
Udgivet: Korean Society for Biochemistry and Molecular Biology 2012
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429811/
https://ncbi.nlm.nih.gov/pubmed/22627808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3858/emm.2012.44.8.054
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