Heregulin-1ß and HER3 in hepatocellular carcinoma: status and regulation by insulin

BACKGROUND: The heregulin-1ß/HER3-driven pathway is implicated in several epithelial malignancies and its blockade is currently undergoing clinical investigation. Paradoxically, the status and the regulation of this pathway is poorly known in hepatocellular carcinoma (HCC). METHODS: Using 85 HCC obt...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Exp Clin Cancer Res
Main Authors: Buta, Corina, Benabou, Eva, Lequoy, Marie, Régnault, Hélène, Wendum, Dominique, Meratbene, Fatiha, Chettouh, Hamza, Aoudjehane, Lynda, Conti, Filomena, Chrétien, Yves, Scatton, Olivier, Rosmorduc, Olivier, Praz, Françoise, Fartoux, Laetitia, Desbois-Mouthon, Christèle
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982118/
https://ncbi.nlm.nih.gov/pubmed/27514687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0402-3
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