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Heregulin-1ß and HER3 in hepatocellular carcinoma: status and regulation by insulin

BACKGROUND: The heregulin-1ß/HER3-driven pathway is implicated in several epithelial malignancies and its blockade is currently undergoing clinical investigation. Paradoxically, the status and the regulation of this pathway is poorly known in hepatocellular carcinoma (HCC). METHODS: Using 85 HCC obt...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Buta, Corina, Benabou, Eva, Lequoy, Marie, Régnault, Hélène, Wendum, Dominique, Meratbene, Fatiha, Chettouh, Hamza, Aoudjehane, Lynda, Conti, Filomena, Chrétien, Yves, Scatton, Olivier, Rosmorduc, Olivier, Praz, Françoise, Fartoux, Laetitia, Desbois-Mouthon, Christèle
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4982118/
https://ncbi.nlm.nih.gov/pubmed/27514687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0402-3
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