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TRIM37, a novel E3 ligase for PEX5-mediated peroxisomal matrix protein import

Most proteins destined for the peroxisomal matrix depend on the peroxisomal targeting signals (PTSs), which require the PTS receptor PEX5, whose deficiency causes fatal human peroxisomal biogenesis disorders (PBDs). TRIM37 gene mutations cause muscle–liver–brain–eye (mulibrey) nanism. We found that...

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Bibliografiska uppgifter
I publikationen:J Cell Biol
Huvudupphovsmän: Wang, Wei, Xia, Zhi-Jie, Farré, Jean-Claude, Subramani, Suresh
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584156/
https://ncbi.nlm.nih.gov/pubmed/28724525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201611170
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