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TRIM37, a novel E3 ligase for PEX5-mediated peroxisomal matrix protein import

Most proteins destined for the peroxisomal matrix depend on the peroxisomal targeting signals (PTSs), which require the PTS receptor PEX5, whose deficiency causes fatal human peroxisomal biogenesis disorders (PBDs). TRIM37 gene mutations cause muscle–liver–brain–eye (mulibrey) nanism. We found that...

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Foilsithe in:J Cell Biol
Main Authors: Wang, Wei, Xia, Zhi-Jie, Farré, Jean-Claude, Subramani, Suresh
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584156/
https://ncbi.nlm.nih.gov/pubmed/28724525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201611170
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