PTPN2 regulates T cell lineage commitment and αβ versus γδ specification

In the thymus, hematopoietic progenitors commit to the T cell lineage and undergo sequential differentiation to generate diverse T cell subsets, including major histocompatibility complex (MHC)–restricted αβ T cell receptor (TCR) T cells and non–MHC-restricted γδ TCR T cells. The factors controlling...

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Publicado en:J Exp Med
Autores principales: Wiede, Florian, Dudakov, Jarrod A., Lu, Kun-Hui, Dodd, Garron T., Butt, Tariq, Godfrey, Dale I., Strasser, Andreas, Boyd, Richard L., Tiganis, Tony
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2017
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584121/
https://ncbi.nlm.nih.gov/pubmed/28798028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20161903
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