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Multilayered Reprogramming in Response to Persistent DNA Damage in C. elegans

DNA damage causally contributes to aging and age-related diseases. Mutations in nucleotide excision repair (NER) genes cause highly complex congenital syndromes characterized by growth retardation, cancer susceptibility, and accelerated aging in humans. Orthologous mutations in Caenorhabditis elegan...

詳細記述

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書誌詳細
出版年:Cell Rep
主要な著者: Edifizi, Diletta, Nolte, Hendrik, Babu, Vipin, Castells-Roca, Laia, Mueller, Michael M., Brodesser, Susanne, Krüger, Marcus, Schumacher, Björn
フォーマット: Artigo
言語:Inglês
出版事項: Cell Press 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583510/
https://ncbi.nlm.nih.gov/pubmed/28854356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.08.028
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