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DAF-16/FoxO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage
Genome maintenance defects cause complex disease phenotypes characterized by developmental failure, cancer susceptibility, and premature aging. It remains poorly understood how DNA damage responses function during organismal development and maintain tissue functionality when DNA damage accumulates w...
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| Publicado no: | Nat Cell Biol |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4250074/ https://ncbi.nlm.nih.gov/pubmed/25419847 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3071 |
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