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DAF-16/FoxO and EGL-27/GATA promote developmental growth in response to persistent somatic DNA damage

Genome maintenance defects cause complex disease phenotypes characterized by developmental failure, cancer susceptibility, and premature aging. It remains poorly understood how DNA damage responses function during organismal development and maintain tissue functionality when DNA damage accumulates w...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Mueller, Michael M., Castells-Roca, Laia, Babu, Vipin, Ermolaeva, Maria A., Müller, Roman-Ulrich, Frommolt, Peter, Williams, Ashley B., Greiss, Sebastian, Schneider, Jennifer I., Benzing, Thomas, Schermer, Bernhard, Schumacher, Björn
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4250074/
https://ncbi.nlm.nih.gov/pubmed/25419847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3071
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