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Genome Instability in Development and Aging: Insights from Nucleotide Excision Repair in Humans, Mice, and Worms
DNA damage causally contributes to aging and cancer. Congenital defects in nucleotide excision repair (NER) lead to distinct cancer-prone and premature aging syndromes. The genetics of NER mutations have provided important insights into the distinct consequences of genome instability. Recent work in...
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| Publicat a: | Biomolecules |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4598778/ https://ncbi.nlm.nih.gov/pubmed/26287260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom5031855 |
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