Hydrogen peroxide induced genomic instability in nucleotide excision repair-deficient lymphoblastoid cells

BACKGROUND: The Nucleotide Excision Repair (NER) pathway specialises in UV-induced DNA damage repair. Inherited defects in the NER can predispose individuals to Xeroderma Pigmentosum (XP). UV-induced DNA damage cannot account for the manifestation of XP in organ systems not directly exposed to sunli...

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Main Authors: Gopalakrishnan, Kalpana, Low, Grace Kah Mun, Ting, Aloysius Poh Leong, Srikanth, Prarthana, Slijepcevic, Predrag, Hande, M Prakash
格式: Artigo
語言:Inglês
出版: BioMed Central 2010
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3022891/
https://ncbi.nlm.nih.gov/pubmed/21176161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9414-1-16
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