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A novel mathematical model of protein-bound uremic toxin kinetics during hemodialysis

Protein-bound uremic toxins (PBUTs) are difficult to remove by conventional hemodialysis; a high degree of protein binding reduces the free fraction of toxins and decreases their diffusion across dialyzer membranes. Mechanistic understanding of PBUT kinetics can open new avenues to improve their dia...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Maheshwari, Vaibhav, Thijssen, Stephan, Tao, Xia, Fuertinger, Doris, Kappel, Franz, Kotanko, Peter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2017
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583320/
https://ncbi.nlm.nih.gov/pubmed/28871178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10981-z
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