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A novel mathematical model of protein-bound uremic toxin kinetics during hemodialysis

Protein-bound uremic toxins (PBUTs) are difficult to remove by conventional hemodialysis; a high degree of protein binding reduces the free fraction of toxins and decreases their diffusion across dialyzer membranes. Mechanistic understanding of PBUT kinetics can open new avenues to improve their dia...

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Bibliografische gegevens
Gepubliceerd in:Sci Rep
Hoofdauteurs: Maheshwari, Vaibhav, Thijssen, Stephan, Tao, Xia, Fuertinger, Doris, Kappel, Franz, Kotanko, Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2017
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5583320/
https://ncbi.nlm.nih.gov/pubmed/28871178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10981-z
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