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The NH(2) terminus regulates voltage-dependent gating of CALHM ion channels

Calcium homeostasis modulator protein-1 (CALHM1) and its Caenorhabditis elegans (ce) homolog, CLHM-1, belong to a new family of physiologically important ion channels that are regulated by voltage and extracellular Ca(2+) (Ca(2+)(o)) but lack a canonical voltage-sensing domain. Consequently, the int...

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Publicat a:Am J Physiol Cell Physiol
Autors principals: Tanis, Jessica E., Ma, Zhongming, Foskett, J. Kevin
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582874/
https://ncbi.nlm.nih.gov/pubmed/28515089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00318.2016
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