A tunable refractive index matching medium for live imaging cells, tissues and model organisms

In light microscopy, refractive index mismatches between media and sample cause spherical aberrations that often limit penetration depth and resolution. Optical clearing techniques can alleviate these mismatches, but they are so far limited to fixed samples. We present Iodixanol as a non-toxic mediu...

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Dettagli Bibliografici
Pubblicato in:eLife
Autori principali: Boothe, Tobias, Hilbert, Lennart, Heide, Michael, Berninger, Lea, Huttner, Wieland B, Zaburdaev, Vasily, Vastenhouw, Nadine L, Myers, Eugene W, Drechsel, David N, Rink, Jochen C
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2017
Soggetti:
Cell Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582871/
https://ncbi.nlm.nih.gov/pubmed/28708059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27240
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