A tunable refractive index matching medium for live imaging cells, tissues and model organisms

In light microscopy, refractive index mismatches between media and sample cause spherical aberrations that often limit penetration depth and resolution. Optical clearing techniques can alleviate these mismatches, but they are so far limited to fixed samples. We present Iodixanol as a non-toxic mediu...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Boothe, Tobias, Hilbert, Lennart, Heide, Michael, Berninger, Lea, Huttner, Wieland B, Zaburdaev, Vasily, Vastenhouw, Nadine L, Myers, Eugene W, Drechsel, David N, Rink, Jochen C
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582871/
https://ncbi.nlm.nih.gov/pubmed/28708059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27240
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