Live-cell visualization of gasdermin D-driven pyroptotic cell death

Pyroptosis is a form of cell death important in defenses against pathogens that can also result in a potent and sometimes pathological inflammatory response. During pyroptosis, GSDMD (gasdermin D), the pore-forming effector protein, is cleaved, forms oligomers, and inserts into the membranes of the...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Rathkey, Joseph K., Benson, Bryan L., Chirieleison, Steven M., Yang, Jie, Xiao, Tsan S., Dubyak, George R., Huang, Alex Y., Abbott, Derek W.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582855/
https://ncbi.nlm.nih.gov/pubmed/28726636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.797217
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