Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation

The transition from transcription initiation to elongation is a key regulatory step in gene expression, which requires RNA polymerase II (pol II) to escape promoter proximal pausing on chromatin. Although elongation factors promote pause release leading to transcription elongation, the role of epige...

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Vydáno v:J Biol Chem
Hlavní autoři: Gates, Leah A., Shi, Jiejun, Rohira, Aarti D., Feng, Qin, Zhu, Bokai, Bedford, Mark T., Sagum, Cari A., Jung, Sung Yun, Qin, Jun, Tsai, Ming-Jer, Tsai, Sophia Y., Li, Wei, Foulds, Charles E., O'Malley, Bert W.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2017
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582839/
https://ncbi.nlm.nih.gov/pubmed/28717009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.802074
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