Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation

The transition from transcription initiation to elongation is a key regulatory step in gene expression, which requires RNA polymerase II (pol II) to escape promoter proximal pausing on chromatin. Although elongation factors promote pause release leading to transcription elongation, the role of epige...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Gates, Leah A., Shi, Jiejun, Rohira, Aarti D., Feng, Qin, Zhu, Bokai, Bedford, Mark T., Sagum, Cari A., Jung, Sung Yun, Qin, Jun, Tsai, Ming-Jer, Tsai, Sophia Y., Li, Wei, Foulds, Charles E., O'Malley, Bert W.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Gene Regulation
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582839/
https://ncbi.nlm.nih.gov/pubmed/28717009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.802074
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