Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation

The transition from transcription initiation to elongation is a key regulatory step in gene expression, which requires RNA polymerase II (pol II) to escape promoter proximal pausing on chromatin. Although elongation factors promote pause release leading to transcription elongation, the role of epige...

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Dades bibliogràfiques
Publicat a:J Biol Chem
Autors principals: Gates, Leah A., Shi, Jiejun, Rohira, Aarti D., Feng, Qin, Zhu, Bokai, Bedford, Mark T., Sagum, Cari A., Jung, Sung Yun, Qin, Jun, Tsai, Ming-Jer, Tsai, Sophia Y., Li, Wei, Foulds, Charles E., O'Malley, Bert W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2017
Matèries:
Gene Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582839/
https://ncbi.nlm.nih.gov/pubmed/28717009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.802074
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