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PKR activation causes inflammation and MMP-13 secretion in human degenerated articular chondrocytes
Osteoarthritis (OA) is a degenerative joint disease affecting a large population of people. Although the elevated expression of PKR (double stranded RNA-dependent protein kinase) and MMP-13 (collagenase-3) have been indicated to play pivotal roles in the pathogenesis of OA, the exact mechanism under...
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| Опубликовано в: : | Redox Biol |
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| Главные авторы: | , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Elsevier
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5582648/ https://ncbi.nlm.nih.gov/pubmed/28869834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.08.011 |
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