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Transient overexpression of Werner protein rescues starvation induced autophagy in Werner syndrome cells
Reduced autophagy may be associated with normal and pathological aging. Here we report a link between autophagy and Werner protein (WRNp), mutated in Werner syndrome, the human premature aging Werner syndrome (WS). WRN mutant fibroblast AG11395 and AG05229 respond weakly to starvation induced autoph...
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| Publicado no: | Biochim Biophys Acta |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5582615/ https://ncbi.nlm.nih.gov/pubmed/25257404 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2014.09.007 |
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