Intracellular adenosine regulates epigenetic programming in endothelial cells to promote angiogenesis

The nucleoside adenosine is a potent regulator of vascular homeostasis, but it remains unclear how expression or function of the adenosine‐metabolizing enzyme adenosine kinase (ADK) and the intracellular adenosine levels influence angiogenesis. We show here that hypoxia lowered the expression of ADK...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Xu, Yiming, Wang, Yong, Yan, Siyuan, Zhou, Yaqi, Yang, Qiuhua, Pan, Yue, Zeng, Xianqiu, An, Xiaofei, Liu, Zhiping, Wang, Lina, Xu, Jiean, Cao, Yapeng, Fulton, David J, Weintraub, Neal L, Bagi, Zsolt, Hoda, Md Nasrul, Wang, Xiaoling, Li, Qinkai, Hong, Mei, Jiang, Xuejun, Boison, Detlev, Weber, Christian, Wu, Chaodong, Huo, Yuqing
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582416/
https://ncbi.nlm.nih.gov/pubmed/28751580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201607066
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