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MYCN induces neuroblastoma in primary neural crest cells
Neuroblastoma (NBL) is an embryonal cancer of the sympathetic nervous system (SNS), which causes 15% of pediatric cancer deaths. High-risk NBL is characterized by N-Myc amplification and segmental chromosomal gains and losses. Owing to limited disease models, the etiology of NBL is largely unknown,...
Kaydedildi:
| Yayımlandı: | Oncogene |
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| Asıl Yazarlar: | , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5582212/ https://ncbi.nlm.nih.gov/pubmed/28459463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.128 |
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