MYCN induces neuroblastoma in primary neural crest cells

Neuroblastoma (NBL) is an embryonal cancer of the sympathetic nervous system (SNS), which causes 15% of pediatric cancer deaths. High-risk NBL is characterized by N-Myc amplification and segmental chromosomal gains and losses. Owing to limited disease models, the etiology of NBL is largely unknown,...

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Publicat a:Oncogene
Autors principals: Olsen, R R, Otero, J H, García-López, J, Wallace, K, Finkelstein, D, Rehg, J E, Yin, Z, Wang, Y-D, Freeman, K W
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2017
Matèries:
Short Communication
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5582212/
https://ncbi.nlm.nih.gov/pubmed/28459463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.128
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