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Alternative NHEJ pathway proteins as components of MYCN oncogenic activity in human neural crest stem cell differentiation: implications for neuroblastoma initiation

Neuroblastoma is a cancer of neural crest stem cell (NCSC) lineage. Signaling pathways that regulate NCSC differentiation have been implicated in neuroblastoma tumorigenesis. This is exemplified by MYCN oncogene targets that balance proliferation, differentiation, and cell death similarly in normal...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Newman, Erika A., Chukkapalli, Sahiti, Bashllari, Daniela, Thomas, Tina T., Van Noord, Raelene A., Lawlor, Elizabeth R., Hoenerhoff, Mark J., Opipari, Anthony W., Opipari, Valerie P.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870584/
https://ncbi.nlm.nih.gov/pubmed/29238067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0004-9
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