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Fertile offspring from sterile sex chromosome trisomic mice
Having the correct number of chromosomes is vital for normal development and health. Sex chromosome trisomy (SCT) affects 0.1% of the human population and is associated with infertility. We show that during reprogramming to induced pluripotent stem cells (iPSC), fibroblasts from sterile trisomic XXY...
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| Pubblicato in: | Science |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5581950/ https://ncbi.nlm.nih.gov/pubmed/28818972 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aam9046 |
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