Cognitive Decline and Brain Amyloid-β Accumulation across 3-years in Adults with Down Syndrome

Adults with Down syndrome (DS) have a high incidence of Alzheimer’s disease (AD), providing a unique opportunity to explore the early, preclinical stages of AD neuropathology. We examined change in brain amyloid-β accumulation via the PET tracer [11C] Pittsburgh compound B (PiB) across two data coll...

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Udgivet i:Neurobiol Aging
Main Authors: Hartley, SL, Handen, BL, Devenny, D, Mihaila, I, Hardison, R, Lao, PJ, Klunk, WE, Bulova, P, Johnson, SC, Christian, BT
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581712/
https://ncbi.nlm.nih.gov/pubmed/28715661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2017.05.019
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