Impact of Amyloid Imaging on Drug Development in Alzheimer’s Disease

Por Mathis, C.A., Lopresti, B.J., Klunk, W.E.
Publicado em 2007

Cognitive Decline and Brain Amyloid-β Accumulation across 3-years in Adults with Down Syndrome

Por Hartley, SL, Handen, BL, Devenny, D, Mihaila, I, Hardison, R, Lao, PJ, Klunk, WE, Bulova, P, Johnson, SC, Christian, BT
Publicado no Neurobiol Aging (2017)

Precuneus amyloid burden is associated with reduced cholinergic activity in Alzheimer disease

Por Ikonomovic, M.D., Klunk, W.E., Abrahamson, E.E., Wuu, J., Mathis, C.A., Scheff, S.W., Mufson, E.J., DeKosky, S.T.
Publicado em 2011

An improved algorithm of white matter hyperintensity detection in elderly adults

Por Ding, T, Cohen, AD, O’Connor, EE, Karim, HT, Crainiceanu, A, Muschelli, J, Lopez, O, Klunk, WE, Aizenstein, HJ, Krafty, R, Crainiceanu, CM, Tudorascu, DL
Publicado no Neuroimage Clin (2019)

Relationship of amyloid beta and neurofibrillary tau deposition in Neurodegeneration in Aging Down Syndrome (NiAD) study at baseline

Por Tudorascu, DL, Laymon, CM, Zammit, M, Minhas, DS, Anderson, SJ, Ellison, PA, Zaman, S, Ances, BM, Sabbagh, M, Johnson, SC, Mathis, CA, Klunk, WE, Handen, BL, Christian, BT, Cohen, AD
Publicado no Alzheimers Dement (N Y) (2020)

Reduced binding of Pittsburgh Compound-B in areas of white matter hyperintensities

Por Goodheart, A.E., Tamburo, E., Minhas, D., Aizenstein, H.J., McDade, E., Snitz, B.E., Price, J.C., Mathis, C.A., Lopez, O.L., Klunk, W.E., Cohen, A.D.
Publicado no Neuroimage Clin (2015)

Anti-Amyloid Effects of Small Molecule Aβ-Binding Agents in PS1/APP Mice

Por Cohen, A.D., Ikonomovic, M.D., Abrahamson, E.E., Paljug, W.R., DeKosky, S.T., Lefterov, I.M., Koldamova, R.P., Shao, L., Debnath, M.L., Mason, N.S., Mathis, C.A., Klunk, W.E.
Publicado em 2009

The effects of normal aging on amyloid-β deposition in nondemented adults with Down syndrome as imaged by [(11)C]PiB

Por Lao, PJ, Betthauser, TJ, Hillmer, AT, Price, JC, Klunk, WE, Mihaila, I, Higgins, AT, Bulova, PD, Hartley, SL, Hardison, R, Tumuluru, RV, Murali, D, Mathis, CA, Cohen, AD, Barnhart, TE, Devenny, DA, Mailick, MR, Johnson, SC, Handen, BL, Christian, BT
Publicado no Alzheimers Dement (2015)

Preclinical trials in autosomal dominant AD: Implementation of the DIAN-TU trial

Por Mills, S.M., Mallmann, J., Santacruz, A.M., Fuqua, A., Carril, M., Aisen, P.S., Althage, M.C., Belyew, S., Benzinger, T.L., Brooks, W.S., Buckles, V.D., Cairns, N.J., Clifford, D., Danek, A., Fagan, A.M., Farlow, M., Fox, N., Ghetti, B., Goate, A.M., Heinrichs, D., Hornbeck, R., Jack, C., Jucker, M., Klunk, W.E., Marcus, D.S., Martins, R.N., Masters, C.M., Mayeux, R., McDade, E., Morris, J.C., Oliver, A., Ringman, J.M., Rossor, M.N., Salloway, S., Schofield, P.R., Snider, J., Snyder, P., Sperling, R.A., Stewart, C., Thomas, R.G., Xiong, C., Bateman, R.J.
Publicado em 2013