The effects of normal aging on amyloid-β deposition in nondemented adults with Down syndrome as imaged by [(11)C]PiB

INTRODUCTION: In Down syndrome (DS), the overproduction of amyloid precursor protein is hypothesized to predispose young adults to early expression of Alzheimer-like neuropathology. METHODS: PET imaging with [(11)C]PiB examined the pattern of amyloid-β deposition in 68 nondemented adults with DS (30...

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Publicado no:Alzheimers Dement
Main Authors: Lao, PJ, Betthauser, TJ, Hillmer, AT, Price, JC, Klunk, WE, Mihaila, I, Higgins, AT, Bulova, PD, Hartley, SL, Hardison, R, Tumuluru, RV, Murali, D, Mathis, CA, Cohen, AD, Barnhart, TE, Devenny, DA, Mailick, MR, Johnson, SC, Handen, BL, Christian, BT
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677061/
https://ncbi.nlm.nih.gov/pubmed/26079411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2015.05.013
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