Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle

The proteasome holoenzyme is activated by its regulatory particle (RP) consisting of two subcomplexes, the lid and the base. A key event in base assembly is the formation of a heterohexameric ring of AAA-ATPases, which is guided by at least four RP assembly chaperones in mammals: PAAF1, p28/gankyrin...

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Publicado no:Mol Cell
Main Authors: Lu, Ying, Wu, Jiayi, Dong, Yuanchen, Chen, Shuobing, Sun, Shuangwu, Ma, Yong-Bei, Ouyang, Qi, Finley, Daniel, Kirschner, Marc W., Mao, Youdong
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580496/
https://ncbi.nlm.nih.gov/pubmed/28689658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2017.06.007
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