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An asymmetric interface between the regulatory particle and core particle of the proteasome
The S. cerevisiae proteasome comprises a 19-subunit regulatory particle (RP) and 28-subunit core particle (CP). To be degraded, substrates must cross the CP-RP interface, a site of complex conformational changes and regulatory events. This interface includes two aligned heteromeric rings: the six AT...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3210322/ https://ncbi.nlm.nih.gov/pubmed/22037170 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2147 |
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