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An asymmetric interface between the regulatory particle and core particle of the proteasome

The S. cerevisiae proteasome comprises a 19-subunit regulatory particle (RP) and 28-subunit core particle (CP). To be degraded, substrates must cross the CP-RP interface, a site of complex conformational changes and regulatory events. This interface includes two aligned heteromeric rings: the six AT...

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Dettagli Bibliografici
Autori principali: Tian, Geng, Park, Soyeon, Lee, Min Jae, Huck, Bettina, McAllister, Fiona, Hill, Christopher P., Gygi, Steven P., Finley, Daniel
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210322/
https://ncbi.nlm.nih.gov/pubmed/22037170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2147
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