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Loss of Apela peptide in mice causes low penetrance embryonic lethality and defects in early mesodermal derivatives
Apela (also known as Elabela, Ende and Toddler) is a small signaling peptide that activates the G protein-coupled receptor Aplnr to stimulate cell migration during zebrafish gastrulation. Here, using CRISPR/Cas9 to generate a null, reporter-expressing allele, we study the role of Apela in the develo...
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| 出版年: | Cell Rep |
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| 主要な著者: | , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5580402/ https://ncbi.nlm.nih.gov/pubmed/28854362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.08.014 |
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