Pancreatic mitochondrial complex I exhibits aberrant hyperactivity in diabetes()

It is well established that NADH/NAD(+) redox balance is heavily perturbed in diabetes, and the NADH/NAD(+) redox imbalance is a major source of oxidative stress in diabetic tissues. In mitochondria, complex I is the only site for NADH oxidation and NAD(+) regeneration and is also a major site for p...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Rep
Main Authors: Wu, Jinzi, Luo, Xiaoting, Thangthaeng, Nopporn, Sumien, Nathalie, Chen, Zhenglan, Rutledge, Margaret A., Jing, Siqun, Forster, Michael J., Yan, Liang-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580358/
https://ncbi.nlm.nih.gov/pubmed/28868496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2017.07.007
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