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Pancreatic mitochondrial complex I exhibits aberrant hyperactivity in diabetes()
It is well established that NADH/NAD(+) redox balance is heavily perturbed in diabetes, and the NADH/NAD(+) redox imbalance is a major source of oxidative stress in diabetic tissues. In mitochondria, complex I is the only site for NADH oxidation and NAD(+) regeneration and is also a major site for p...
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| Publicat a: | Biochem Biophys Rep |
|---|---|
| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5580358/ https://ncbi.nlm.nih.gov/pubmed/28868496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrep.2017.07.007 |
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