Reversible inactivation of dihydrolipoamide dehydrogenase by mitochondrial hydrogen peroxide

Under oxidative stress conditions, mitochondria are the major site for cellular production of reactive oxygen species (ROS) such as superoxide anion and H(2)O(2) that can attack numerous mitochondrial proteins including dihydrolipoamide dehydrogenase (DLDH). While DLDH is known to be vulnerable to o...

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Bibliografiske detaljer
Main Authors: Yan, Liang-Jun, Sumien, Nathalie, Thangthaeng, Nopporn, Forster, Michael J.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690130/
https://ncbi.nlm.nih.gov/pubmed/23205777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10715762.2012.752078
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