Sparse conserved under-methylated CpGs are associated with high-order chromatin structure

BACKGROUND: Whole-genome bisulfite sequencing (WGBS) is the gold standard for studying landscape DNA methylation. Current computational methods for WGBS are mainly designed for gene regulatory regions with multiple under-methylated CpGs (UMCs), such as promoters and enhancers. RESULTS: To reliably p...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genome Biol
Prif Awduron: Lin, Xueqiu, Su, Jianzhong, Chen, Kaifu, Rodriguez, Benjamin, Li, Wei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2017
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580327/
https://ncbi.nlm.nih.gov/pubmed/28859663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1296-x
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