A 13-gene expression-based radioresistance score highlights the heterogeneity in the response to radiation therapy across HPV-negative HNSCC molecular subtypes

BACKGROUND: Radiotherapy for head and neck squamous cell carcinomas (HNSCC) is associated with a substantial morbidity and inconsistent efficacy. Human papillomavirus (HPV)-positive status is recognized as a marker of increased radiosensitivity. Our goal was to identify molecular markers associated...

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Detalhes bibliográficos
Publicado no:BMC Med
Main Authors: Foy, Jean-Philippe, Bazire, Louis, Ortiz-Cuaran, Sandra, Deneuve, Sophie, Kielbassa, Janice, Thomas, Emilie, Viari, Alain, Puisieux, Alain, Goudot, Patrick, Bertolus, Chloé, Foray, Nicolas, Kirova, Youlia, Verrelle, Pierre, Saintigny, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5580222/
https://ncbi.nlm.nih.gov/pubmed/28859688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-017-0929-y
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