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Serum amyloid A inhibits dendritic cell differentiation by suppressing GM-CSF receptor expression and signaling
In this study, we report that an acute phase reactant, serum amyloid A (SAA), strongly inhibits dendritic cell differentiation induced by GM-CSF plus IL-4. SAA markedly decreased the expression of MHCII and CD11c. Moreover, SAA decreased cell surface GM-CSF receptor expression. SAA also decreased th...
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| Pubblicato in: | Exp Mol Med |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5579511/ https://ncbi.nlm.nih.gov/pubmed/28857084 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2017.120 |
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